Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

By Masae Kinoshita Hitoshi Okamoto

Source: cell

4/26/2023

Switching behaviors from aggression to submission in losers at the end of conspecific social fighting is essential to avoid serious injury or death. We have previously shown that the experience of defeat induces a loser-specific potentiation in the habenula (Hb)-interpeduncular nucleus (IPN) and show here that this is induced by acetylcholine.

Calcium imaging and electrophysiological recording using acute brain slices from winners and losers of fighting behavior in zebrafish revealed that the ventral IPN (vIPN) dominates over the dorsal IPN in the neural response to Hb stimulation in losers. We also show that GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits on the postsynaptic membrane increased in the vIPN of losers.

Continue...

News Id		Source	Stamp	country
3976	Manitoba fish co-op fined for illegally selling to U.S.	CBC News	2013-05-27	CA
3977	Could enormous Baja amberjack have been a world record?	petethomasoutdoors	2013-05-22	MX
3978	Davenport anglers busted for 332 fish over limit	qctimes	2013-05-23	US
3979	Angler catches same giant carp he hooked 14 years ago but this time it's DOUBLE the size	dailymail	2013-05-20	UK
3980	Sainsbury’s admit ‘mislabelling’ Scottish salmon	scotsman	2013-05-21	UK
3981	An Open Letter to Animal Planet: Learn The Difference Between Real and Fake Monsters	scientificamerican	2013-05-15	US
3982	Scientist to dye Missouri River red for fish larvae study	fourstateshomepage	2021-05-03	US
3983	Koi can come in a wide variety of colors	ksl	2021-04-27	US
3984	Lamprey numbers predict promising comeback for spooky blood-sucking fish	abc	2021-04-28	AU
3985	Seaweed supplement claimed to quadruple immune response of farmed fish	newatlas	2021-04-29	US
3986	Record-breaking 103lb cod would provide 200 fish suppers	telegraph	2013-05-13	UK
3987	Underwater robot seeks out endangered sturgeons	newatlas	2013-05-07	US
3988	Fish farms allied with government, activists say	Times Colonist	2013-05-04	CA
3989	U.S. fishing boat collides with Canadian navy ship	ctvnews	2013-04-23	CA
3990	Salmonid Spawning Runs and Estimated Ova Production in Normandale Creek of Lake Erie	Journal of Great Lakes Research	1985-01-01	CA
3991	98-year-old man catches dream fish on last day of season	komu	2021-04-29	US
3992	‘Real life river monster’: 240-pound fish believed to be over 100 years old caught in Detroit River	wnct	2021-04-22	US
3993	Several anglers charged for fishing along Ganaraska River in Port Hope, Ont	Global News	2021-04-26	CA
3994	Sizewell C nuclear plant could kill 500m fish, campaigners say	theguardian	2021-04-28	UK
3995	Tulsa Man Catches A Fish Not Common To Oklahoma Waters	news9	2013-04-23	UK
3996	Kona catch of 958-pound blue marlin could be a world record	petethomasoutdoors	2013-04-18	US
3997	After 35 years a golden oldie turns up his fins: Britain's oldest goldfish, Splash, loses lifelong tank buddy, Splish	dailymail	2013-04-18	UK
3998	Some fish species, including cod, may never bounce back: study	ctvnews	2013-04-18	CA
3999	Submarine maker wants to replace humans who fish	China Daily	2013-04-09	CN
4000	Kan. couple catches record-breaking catfish	fox4kc	2013-04-09	US

159 of [218 - pages.]