Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

By Masae Kinoshita Hitoshi Okamoto

Source: cell

4/26/2023

Switching behaviors from aggression to submission in losers at the end of conspecific social fighting is essential to avoid serious injury or death. We have previously shown that the experience of defeat induces a loser-specific potentiation in the habenula (Hb)-interpeduncular nucleus (IPN) and show here that this is induced by acetylcholine.

Calcium imaging and electrophysiological recording using acute brain slices from winners and losers of fighting behavior in zebrafish revealed that the ventral IPN (vIPN) dominates over the dorsal IPN in the neural response to Hb stimulation in losers. We also show that GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits on the postsynaptic membrane increased in the vIPN of losers.

Continue...

News Id		Source	Stamp	country
476	Warming seas push Indias fishers into distant, and more dangerous, waters	mongabay	2024-04-23	IN
477	Douglas County man arrested after thousands of hatchery fish poisoned	kobi5	2024-04-25	US
478	Navigating the rise in conflicts between humans and fishing cats in Bangladesh	mongabay	2024-04-25	BD
479	How local fishermen found a group of blackfin tuna while fishing in Gulf of Mexico	Bradenton Herald	2024-04-21	US
480	Unlike Earnest Hemingway's epic tale "The Old Man and the Sea," the sharks did not come along and eat the giant. Though, after	Asbury Park Press	2024-04-22	US
481	117 operations to tackle fish bombing in Sabah since 2021	nst	2024-04-24	MY
482	Woman catches 30-pound koi fish in Texas lake	klfy	2024-04-26	US
483	Fewer fish and more rules lead to illegal catches, Italian fishers say	mongabay	2024-04-26	IT
484	BC salmon farmer hopes algae can replace wild fish as feed ingredient	mycomoxvalleynow	2024-04-27	CA
485	The Moon brings a wild but precarious fish orgy to California's beaches	BBC News	2024-04-19	US
486	More California dog owners advised to be aware of salmon poisoning disease	ktla	2024-04-23	US
487	Dead Fish Suddenly Found in California Lake Raises Alarms	msn	2024-04-30	US
488	Angler who posed with giant salmon for proud Facebook picture is netted for illegal fishing and fined nearly £1,000	Daily Mail	2024-03-16	UK
489	The patin are gone: the freshwater war against suckermouth catfish	freemalaysiatoday	2024-04-13	MY
490	Nature reserve to be created next to new nuclear plant that will kill tonnes of fish a year	telegraph	2024-04-16	UK
491	San Antonio angler reels in 30-inch unusual catch in neighborhood pond	mysanantonio	2024-04-13	US
492	Girls record catfish sparks controversy	usatoday	2024-04-18	US
493	Stolen tropical fish returned to Ottawa Valley restaurant	CBC News	2024-04-19	CA
494	Soft sea creature – with red scaleless body — discovered in Japan	miamiherald	2024-04-19	JP
495	This invasive alien fish is threatening the Guadalquivir ecosystem	d1softballnews	2024-04-14	US
496	Thai Officials Warn Releasing Fish Into Nature Wont Bring Good Karma	yahoo	2024-04-15	TH
497	Truck crash spills live salmon into wrong Oregon riverScientists push new paradigm of animal consciousness, saying even insects	nbcnews	2024-04-19	US
498	Raising fish and a workforce with an economic development grant	alleghenyfront	2024-04-19	US
499	Indigenous Marine Scientist Studies Fish Feeding Evolution in Panama	smithsonianmag	2024-04-19	US
500	Boops, hums and farts: The mysterious world of fish communication	BBC News	2024-04-19	US