Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

By Masae Kinoshita Hitoshi Okamoto

Source: cell

4/26/2023

Switching behaviors from aggression to submission in losers at the end of conspecific social fighting is essential to avoid serious injury or death. We have previously shown that the experience of defeat induces a loser-specific potentiation in the habenula (Hb)-interpeduncular nucleus (IPN) and show here that this is induced by acetylcholine.

Calcium imaging and electrophysiological recording using acute brain slices from winners and losers of fighting behavior in zebrafish revealed that the ventral IPN (vIPN) dominates over the dorsal IPN in the neural response to Hb stimulation in losers. We also show that GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits on the postsynaptic membrane increased in the vIPN of losers.

Continue...

News Id		Source	Stamp	country
2301	SA fishers hopeful of end to snapper ban in new year	9news	2022-10-17	AU
2302	Can You Catch More Fish When the Water Is Spinning?	noaa	2022-10-24	US
2303	Плотва холодной воды	Охотники.ру	2022-10-27	RU
2304	Man catches record hybrid striped bass in New Jersey: 'Trolling in 20 feet'	foxnews	2022-10-27	US
2305	Желтоносовские караси	Охотники.ру	2022-10-26	RU
2306	Queensland government to study fish ecosystems after back-to-back La Niña events	ABC Southern Qld	2022-10-09	AU
2307	Holy Mola: 3-ton ‘Hummer-sized’ sunfish sets record for biggest fish ever	nypost	2022-10-17	PT
2308	Mysterious breeding habits of aquarium fish vex experts	nypost	2022-10-20	ID
2309	Earthquake looms as anglers land doomsday fish: ‘We are all going to die!’	nypost	2022-10-10	MX
2310	Fish GPS? Scientists find goldfish go farther next to certain stripes	theguardian	2022-10-12	US
2311	Fairview Heights family invested in a Florida fishing business	ksdk	2022-10-13	US
2312	Технология микро-AUV держит в тайне секретные подводные миссии, наблюдение и разведку	building-tech	2022-08-30	CA
2313	n the front line of the fish for sex trade ‘spiralling out of control’	telegraph	2022-10-14	UK
2314	Angler sets state record with ‘monster’ hybrid trout	wtok	2022-10-15	US
2315	Giant 900lb tuna biggest fish caught in Welsh waters	BBC News	2022-10-10	US
2316	Fish feel 'pain, stress and anxiety': Organisation introduces proposal for their 'humane slaughter'	wionews	2022-10-10	IN
2317	A Giant Sunfish In the Azores Weighed In as the Heaviest Bony Fish On Record	theinertia	2022-10-13	US
2318	Colorado fishermen cited for poaching 460 pounds of salmon in Northern Michigan	mlive	2022-10-14	US
2319	A shock of cold water could help control exotic fish in Grand Canyon	Arizona Public Radio	2022-10-14	US
2320	Switching from sturgeon – a look at global salmon and trout roe consumption	The Fish Site	2022-10-22	US
2321	Clean Water Act at 50: Environmental Gains, Challenges Unmet	Associated Press	2022-10-17	US
2322	Tiny Tennessee Fish Protected, but US Has Yet to Say Where	Associated Press	2022-10-21	US
2323	Владимирская макала	Охотники.ру	2022-10-21	RU
2324	Award-winning — plastic-eating robo-fish is finally here to rid our waters of waste	interestingengineering	2022-10-22	US
2325	Neurotoxic predatory	aked-science	2022-10-20	US