Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

By Masae Kinoshita Hitoshi Okamoto

Source: cell

4/26/2023

Switching behaviors from aggression to submission in losers at the end of conspecific social fighting is essential to avoid serious injury or death. We have previously shown that the experience of defeat induces a loser-specific potentiation in the habenula (Hb)-interpeduncular nucleus (IPN) and show here that this is induced by acetylcholine.

Calcium imaging and electrophysiological recording using acute brain slices from winners and losers of fighting behavior in zebrafish revealed that the ventral IPN (vIPN) dominates over the dorsal IPN in the neural response to Hb stimulation in losers. We also show that GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits on the postsynaptic membrane increased in the vIPN of losers.

Continue...

News Id		Source	Stamp	country
2226	Scientists figure out why fish look downwards when swimming in rivers	news9live	2022-11-06	IN
2227	Victory Farms donates tilapia fingerlings to small-scale producers	The Fish Site	2022-11-25	KE
2228	New IoT sensor sheds light on shellfish growers’ farm conditions	The Fish Site	2022-11-28	PT
2229	FDA puts AquaBounty’s genetically engineered salmon back under the spotlight	The Fish Site	2022-11-28	US
2230	Trial leverages AI and imaging technology to identify the best delousing cleaner fish	The Fish Site	2022-11-28	UK
2231	Washington Bans Fish-Farming Net Pens	Associated Press	2022-11-18	US
2232	Lawsuit Looms Over Tiny Rare Fish in Drought-Stricken West	Associated Press	2022-11-23	US
2233	Пока не затвердела вода	Охотники.ру	2022-11-15	RU
2234	С фидером в период первых заморозков	Охотники.ру	2022-11-21	RU
2235	Fishermen take case against paying for monitors to Supreme Court	pressherald	2022-11-10	US
2236	Sewage on the riverbed blamed for 'anglers catching more tampons than fish' in Shrewsbury	shropshirestar	2022-11-11	UK
2237	Mom shares photos of creature that 'startled' her and daughter on fishing trip	yahoo	2022-11-10	US
2238	Scientists Making a "Nightmarish Coffee" From Parasitic Fish	bestlifeonline	2022-11-04	US
2239	The 'Achilles Heel' Of Fish Farming: Trends In The Development Of Technology To Replace Fishmeal	forbes	2022-11-07	US
2240	New Bizarre Fish With Glowing Eyes Found During Expedition To Cocos Islands	Live Science	2022-11-11	AU
2241	A rare, brain-eating amoeba is spreading across the US	interestingengineering	2022-11-25	US
2242	The business end of a wolf eel	twitter	2022-11-22	CA
2243	British angler catches massive 30 kg goldfish, netizens are stunned	hindustantimes	2022-11-22	FR
2244	Washington Bans Fish-Farming Net Pens, Citing Salmon Threat	Associated Press	2022-11-18	US
2245	Three-metre 'rare' tuna fish found washed up on Lincolnshire beach by dog walker	lincolnshirelive	2022-10-28	UK
2246	Japanese restaurant lets customers catch their own fish to cook	hindustantimes	2022-10-29	JP
2247	Настоящий рыбацкий день рождения	Охотники.ру	2022-11-09	RU
2248	At least 6% of global fishing ‘probably illegal’ as ships turn off tracking devices	theguardian	2022-11-02	UK
2249	Diving family from Mathews helping with invasive lionfish—by eating them	gazettejournal	2022-11-02	US
2250	Experts struggling to save tiny 'bejeweled' fish from extinction	kxxv	2022-10-30	US