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| Pollution from mining in the region has caused great concern among environmentalists because several rare species inhabit the river. Some mussels were reintroduced to the Cleveland, Virginia area from outside the state in the early 2000s after pollution in the 20th century wiped out much of the population. |
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 | Source : | Buckhorn Mountain near Tazewell |  |
| Lattitude: | 37.1413879394531 | |
| Longitude: | -81.4613876342773 | |
| Elevation: | 840 | [m] | | Location: | Buckhorn Mountain near Tazewell | |
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 | Mouth : | | |
| Lattitude: | 35.8633346557617 | |
| Longitude: | -84.5316696166992 | |
| Elevation: | 226 | [m] | | Location: | Tennessee River | |
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